In 2001, Hagan Bayley’s lab at Texas A&M demonstrated a limited sequencing method based on the observation that correctly and incorrectly paired DNA bases disrupted nanopore current to different extents. They tethered a short piece of DNA with a few unknown bases to the entrance of the nanopore, then added other short DNA strands with different bases at the position corresponding to the unknown base on the tethered strand. By looking at which base produced the disruption corresponding to a perfect match, they could guess the unknown nucleotide.
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Perhaps most significantly, Apple has raised prices on its entire MacBook Pro lineup. The 14-inch M5 model previously started at $1,599; it’s now priced at $1,699. At least you’re getting something for that cash, as Apple has doubled its base storage to 1TB.